Watch and wait after careful surgical treatment and staging in well-differentiated early ovarian cancer

We analyzed results of laparoscopic surgical treatment of 349 patients with ovarian tumors. Before surgery besides standard examination ultrasonography of pelvis and Ca-125 estimation was performed. After comparing of preoperative diagnosis with histopatological report was identified low sensitivity and specificity of ultrasonography and Ca-125 for assessment of tumor malignancy potential (32,35 %, 31,82 % and 72,55 %, 68,36 % respectively). It was concluded that nowadays the only method of early ovarian cancer detection is surgical treatment of patients with ovarian tumors, who have ultrasonography malignancy markers and increased Ca-125 level.

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Surgical treatment of early ovarian cancer with compartmental resection of regional lymphatic network and indocyanine-green-guided targeted compartmental lymphadenectomy (TCL, paraaortic part)

Journal of Gynecologic Oncology ◽

10.3802/jgo.2017.28.e41 ◽

2017 ◽

Vol 28 (3) ◽

Cited By ~ 4

Author(s):

Rainer Kimmig ◽

Paul Buderath ◽

Pawel Mach ◽

Peter Rusch ◽

Bahriye Aktas

Keyword(s):

Ovarian Cancer ◽

Surgical Treatment ◽

Indocyanine Green ◽

Early Ovarian Cancer ◽

Compartmental Resection ◽

Lymphatic Network

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Immunoreactive score of Ep-CAM might predict survival in early ovarian cancer patients

Geburtshilfe und Frauenheilkunde ◽

10.1055/s-0031-1286464 ◽

2011 ◽

Vol 71 (08) ◽

Author(s):

MJ Battista ◽

J Steetskamp ◽

N Mantai ◽

S Gebhard ◽

C Cotarelo ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Patients ◽

Early Ovarian Cancer

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ANALYSIS OF UTERINE LAVAGE FOR EARLY OVARIAN CANCER DETECTION

10.26226/morressier.5fa3ee5d55b1fd4cc4dd9435 ◽

2020 ◽

Author(s):

Diana Žilovič ◽

Rūta Čiurlienė ◽

Ieva Vaicekauskaitė ◽

Rasa Sabaliauskaitė ◽

Sonata Jarmalaitė

Keyword(s):

Ovarian Cancer ◽

Cancer Detection ◽

Early Ovarian Cancer ◽

Uterine Lavage

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ROLE OF ULTRASOUND IN THE DETECTION OF RECURRENT OVARIAN CANCER

UZBEK MEDICAL JOURNAL ◽

10.26739/2181-0664-2020-6-4 ◽

2020 ◽

Vol 6 (1) ◽

pp. 23-31

Author(s):

M. Alisherova ◽

◽

M. Ismailova

Keyword(s):

Ovarian Cancer ◽

Surgical Treatment ◽

Reproductive System ◽

Malignant Tumors ◽

Recurrent Ovarian Cancer ◽

Primary Diagnosis ◽

Female Reproductive System

Currently, there are no standard approaches to monitoring patients with ovarian cancer (OC). While the role of ultrasound (US) has been identified in the primary diagnosis of OS, it is still controversial during the subsequent surgical treatment of OC. In world statistics, ovarian cancer is consistently among the four main localizations of malignant tumors of the female reproductive system, along with tumors of the breast, body and cervix.

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Clinical outcomes of patients with endometrioid epithelial ovarian cancer following surgical treatment

Journal of Surgical Oncology ◽

10.1002/jso.26597 ◽

2021 ◽

Author(s):

Paulina Cybulska ◽

Jill Tseng ◽

Qin C. Zhou ◽

Alexia Iasonos ◽

Deborah F. Delair ◽

...

Keyword(s):

Ovarian Cancer ◽

Surgical Treatment ◽

Epithelial Ovarian Cancer ◽

Clinical Outcomes

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Fertility preservation in women with early ovarian cancer

Hormone Molecular Biology and Clinical Investigation ◽

10.1515/hmbci-2020-0026 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Daniel Necula ◽

Daria Istrate ◽

Jérôme Mathis

Keyword(s):

Ovarian Cancer ◽

Fertility Preservation ◽

Low Grade ◽

Term Survival ◽

Organizational Issues ◽

Fertility Sparing Surgery ◽

Fertility Sparing ◽

Early Ovarian Cancer ◽

Reproductive Techniques

AbstractFertility preservation is an important option to consider for young women with low-grade early ovarian cancer. Fertility-sparing surgery (“FSS”) permits the conservation of the uterus and one of the ovaries. This technique is considered safe for stages IA G1, G2 and probably safe for IC G1 epithelial and non-epithelial ovarian cancers. There are still uncertainties and FSS is not fully accepted for stage IC G1, G2 and clear cell carcinoma. The difficulty in choosing the best option lies in the fact that there is a lack of prospective randomized studies, due to ethical and organizational issues. Retrospective studies and reviews showed reassuring results for FSS in terms of relapse and long term survival. The spontaneous pregnancy rate seems to decrease after FSS, but chemotherapy does not seem to have an impact on fertility rates. Compared with the general population, assisted reproductive techniques are considered safe and with similar fertility results.

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Systematic review of adjuvant therapy for early stage (epithelial) ovarian cancer

International Journal of Gynecological Cancer ◽

10.1136/ijgc-00009577-200307000-00001 ◽

2003 ◽

Vol 13 (4) ◽

pp. 395-404 ◽

Cited By ~ 7

Author(s):

B. Winter-Roach ◽

L. Hooper ◽

H. Kitchener

Keyword(s):

Systematic Review ◽

Ovarian Cancer ◽

Adjuvant Chemotherapy ◽

Adjuvant Therapy ◽

Early Stage ◽

Meta Analysis ◽

Disease Free Survival ◽

Significant Difference ◽

Well Differentiated ◽

Platinum Chemotherapy

A systematic review and meta analysis has been undertaken in order to evaluate the effectiveness of adjuvant therapy following surgery for early ovarian cancer. Trials reported since 1990 have been of a higher quality enabling a meta analysis of adjuvant chemotherapy vs adjuvant radiotherapy and a meta analysis of adjuvant chemotherapy vs observation. There was no significant difference between radiotherapy and chemotherapy, though these comprised studies which demonstrated considerable heterogeneity. Chemotherapy did confer significant benefit over observation in terms of both overall and disease free survival. Except for women in whom adequate surgical staging has revealed well differentiated disease confined to one or both ovaries with intact capsule, platinum chemotherapy should be offered to reduce risk of recurrence.

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